E. Treatments of Obesity and Sleep Disorder
1. According to the study of "Quantification of sleep behavior and of its impact on the cross-talk between the brain and peripheral metabolism" by Hanlon EC, Van Cauter E., posted in PubMed, researchers indicated that... Simultaneously, average sleep times have progressively decreased. Recently, evidence from both laboratory and epidemiologic studies has suggested that insufficient sleep may stimulate overeating and thus play a role in the current epidemic of obesity and diabetes,.... The findings provide evidence that sleep restriction does indeed impair glucose metabolism and alters the cross-talk between the periphery and the brain, favoring excessive food intake. A better understanding of the adverse effects of sleep restriction on the CNS control of hunger and appetite may have important implications for public health.
2. In a study of "Sleep apnea and obesity" by Yu JC, Berger P 3rd., posted in PubMed, researchers wrote that Perhaps, the strongest observational evidence to support a link between sleepapnea and obesity is the similarity in age distribution of symptomatic sleep apnea and metabolic syndrome. The putative causal links between sleep apnea and each individual component of the metabolic syndrome have been extensively evaluated and have implicated bidirectional causality in certain metabolic conditions, such as obesity and sleep apnea, sleep apnea and diabetes mellitus, and obesity and diabetes mellitus. These studies collectively suggest that even modest weight loss improves OSA, and positively affects both metabolic and cardiovascular risk profiles.
3. in the abstract of the study of "Pharmacological treatment of obstructive sleep apnea", by Abad VC, Guilleminault C., posted in PubMed,researchers wrote that Obstructive sleepapnea (OSA) is a growing public health hazard fueled by the obesity epidemic and an aging population. Untreated sleepapnea can result in significant consequences both in the short-term and long-term. We need to educate the public to recognize the symptoms of sleepapnea and to publicize that effective treatments are available. Positive airway pressure therapy remains the gold standard currently in treating OSA. Alternative treatments include an oral appliance or surgical options. This paper discusses the pharmacologic treatment of sleep apnea: goals include medications to address the ventilatory control of breathing, treat co-morbid diseases, treat associated health problems/complaints, address special issues, such as anesthetic precautions, and propose future targets.
- << Indietro